Insulin and Insulin-like Growth Factor signalling (IGF) pathways and cancer / Wan Iryani Wan Ismail, Mohd Nazri Abu, Muhammad Ashraf Mohd Salleh, Izmil Haikal Zainol and Rosmadi Mohd Yusoff

Abu, Mohd Nazri and Mohd Salleh, Muhammad Ashraf and Zainol, Izmil Haikal and Mohd Yusoff, Rosmadi (2013) Insulin and Insulin-like Growth Factor signalling (IGF) pathways and cancer / Wan Iryani Wan Ismail, Mohd Nazri Abu, Muhammad Ashraf Mohd Salleh, Izmil Haikal Zainol and Rosmadi Mohd Yusoff. Esteem Academic Journal, 9 (2). pp. 87-95. ISSN 1675-7939

Abstract

Cell signalling is part of a strategy in drug discovery. Among the focus is by studying the insulin and insulin-like growth factor (IGF1R) signalling pathways. The molecular mechanism of insulin and IGF1R signalling pathways have been studied extensively. Both pathways are vital in many of the mechanisms in human body particularly in regulating the metabolism and cell growth. Besides, both pathways have been found to be involved in numerous diseases such as in various types of cancer. This review briefly revealed the information on the pathways, their correlations and current findings in cancer study.

Metadata

Item Type: Article
Creators:
Creators
Email / ID Num.
Abu, Mohd Nazri
UNSPECIFIED
Mohd Salleh, Muhammad Ashraf
UNSPECIFIED
Zainol, Izmil Haikal
UNSPECIFIED
Mohd Yusoff, Rosmadi
UNSPECIFIED
Divisions: Universiti Teknologi MARA, Pulau Pinang
Journal or Publication Title: Esteem Academic Journal
UiTM Journal Collections: UiTM Journal > ESTEEM Academic Journal (EAJ)
ISSN: 1675-7939
Volume: 9
Number: 2
Page Range: pp. 87-95
Keywords: cancers; cell signalling; insulin; insulin-like growth factor signalling pathways
Date: 2013
URI: https://ir.uitm.edu.my/id/eprint/8912
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8912

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