The invisible evil twin of an adrenal adenoma / Aimi Fadilah M … [et al.]

Mohamad, Aimi Fadilah and Mohamed Shah, Fatimah Zaherah and Zainordin, Nur Aisyah and Eddy Warman, ur 'Aini and Ab Mumin, Nazimah and Omar, Effat and Abdul Ghani, Rohana (2019) The invisible evil twin of an adrenal adenoma / Aimi Fadilah M … [et al.]. Journal of Clinical and Health Sciences, 4 (1). pp. 1-6. ISSN 0127-984X

Abstract

Primary aldosteronism (PA) causes a persistently elevated blood pressure (BP) due to excessive release of the hormone aldosterone from the adrenal glands. Classically, it is called Conn’s syndrome and is described as the triad of hypertension and hypokalemia with the presence of unilateral adrenal adenoma. It can be cured with surgical resection of the aldosterone-secreting adenoma leading to resolution of hypertension, hypokalemia and increased cardiovascular risk associated with hyperaldosteronism. We present a case of a man with previous ischemic heart disease (IHD) who presented with resistant hypertension. Investigations for secondary causes of hypertension revealed an elevated aldosterone level and saline suppression test confirmed the diagnosis of PA. Radiological examination revealed a left adrenal adenoma and a normal right adrenal gland. However, adrenal venous sampling showed lateralization of aldosterone secretion towards the right. He subsequently underwent a laparoscopic right adrenalectomy which improved his BP control promptly. This case highlights the importance of recognizing the need to investigate for secondary causes of hypertension. It also underscores the importance of dynamic tests, which may not be easily accessible to most clinicians but should pursue, to allow a definitive diagnosis and effective treatment.

Metadata

Item Type: Article
Creators:
Creators
Email / ID Num.
Mohamad, Aimi Fadilah
aimimohamad1@gmail.com
Mohamed Shah, Fatimah Zaherah
UNSPECIFIED
Zainordin, Nur Aisyah
UNSPECIFIED
Eddy Warman, ur 'Aini
UNSPECIFIED
Ab Mumin, Nazimah
UNSPECIFIED
Omar, Effat
UNSPECIFIED
Abdul Ghani, Rohana
UNSPECIFIED
Subjects: Q Science > QP Physiology
Q Science > QP Physiology > Cerebral cortex
Q Science > QP Physiology > Cerebral cortex > Auditory cortex. Sensorimotor cortex
Divisions: Universiti Teknologi MARA, Selangor > Puncak Alam Campus > Faculty of Medicine
Journal or Publication Title: Journal of Clinical and Health Sciences
UiTM Journal Collections: UiTM Journal > Journal of Clinical and Health Sciences (JCHS)
ISSN: 0127-984X
Volume: 4
Number: 1
Page Range: pp. 1-6
Keywords: primary aldosteronism, hypertension, adrenal adenoma, adrenal vein sampling
Date: June 2019
URI: https://ir.uitm.edu.my/id/eprint/30048
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