Antifungal activity of artocarpus altilis leaf extract / Faridah Boiran

Boiran, Faridah (2016) Antifungal activity of artocarpus altilis leaf extract / Faridah Boiran. [Student Project] (Unpublished)

Abstract

The study was aimed to determine the antifungal activity of Artocarpus altilis leaf extract and to compare the effectiveness of leaf extract in three different types of solvent (ethanol, chloroform and water). Antifungal activity was tested against four pathogenic fungi (Aspergillus fumigatus, Aspergillus niger, Tricophyton sp and Malassezia sp) using disc diffusion method by indicating the
presence of the clear zone of inhibition around discs impregnated with different concentration of extract (12.5, 25, 50 and 100 mg/ml). The positive control used was fluconazole and negative control was the solvent itself
without extract. The result showed that water extract was the most effective compared to other solvents used (ethanol and chloroform) indicated by the highest inhibitory activity against the tested fungi. The only two fungi were inhibited (Aspergillus fumigatus and Aspergillus niger) at concentration 25, 50 and 100 mg/ml with concentration dependent manner. Aspergillus species were
more susceptible as indicated by the largest diameter of inhibition zone at 13.33 mm of diameter against Aspergillus fumigatus followed by Aspergillus
niger at 12.67 mm, while Tricophyton sp and Malassezia sp showed resistant to all different concentration of extracts. The result suggested that the Artocarpus altilis leaf extracts have the promising of low therapeutic potential against certain fungi.

Metadata

Item Type: Student Project
Creators:
Creators
Email / ID Num.
Boiran, Faridah
UNSPECIFIED
Subjects: Q Science > QR Microbiology
Q Science > QR Microbiology > Immunology > Fungal antigens
Divisions: Universiti Teknologi MARA, Negeri Sembilan > Kuala Pilah Campus > Faculty of Applied Sciences
Keywords: Antifungal activity, of artocarpus altilis leaf extract, UiTM Negeri Sembilan
Date: 2016
URI: https://ir.uitm.edu.my/id/eprint/24431
Edit Item
Edit Item

Download

[thumbnail of PPb_FARIDAH BOIRAN AS N 16_5.pdf] Text
PPb_FARIDAH BOIRAN AS N 16_5.pdf

Download (125kB)

Digital Copy

Digital (fulltext) is available at:

Physical Copy

Physical status and holdings:
Item Status:

ID Number

24431

Indexing

Statistic

Statistic details