A study on bioactive constituents of Myrmecodia Platytyrea subsp. antoinii (Becc.) Huxley & Jebb / Nur Fadhilah Mohamad Haris

Mohamad Haris, Nur Fadhilah (2014) A study on bioactive constituents of Myrmecodia Platytyrea subsp. antoinii (Becc.) Huxley & Jebb / Nur Fadhilah Mohamad Haris. Masters thesis, Universiti Teknologi MARA.

Abstract

The Myrmecodia genus (ant plant) is traditionally used to prevent and cure the cancer, heart problems and other serious diseases. Although there are many medicinal effects claimed, unfortunately there were only a few reports on the chemical isolation of the constituents on Myrmecodia platytyrea subsp. antoinii (Becc.) Huxley & Jebb. All the extracts from this plant were tested using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) method. The ethyl acetate (EA) extract was the most potent with the EC₅₀ value, 32.91 ± 2.23 |μg/mL. The potent extract in DPPH test was further fractionated using MPLC, which gave a total of 8 fractions (F1 - F8). All the fractions were tested using DPPH method and the F5 was the most potent with the EC₅₀ value, 21.57 ± 1.40 | μg/mL.The ferrous ion chelating (FIC) activity also was tested on EA extract and the result was negative…

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Item Type: Thesis (Masters)
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CreatorsID Num. / Email
Mohamad Haris, Nur FadhilahUNSPECIFIED
Divisions: Universiti Teknologi MARA, Shah Alam > Faculty of Pharmacy
Item ID: 18467
Uncontrolled Keywords: Cancer; Ant plant; Myrmecodia Platytyrea subsp. antoinii
URI: http://ir.uitm.edu.my/id/eprint/18467

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