Potassium aluminium sulphate (Alum) inhibits growth of human axillary malodor-producing skin flora in vitro / Hassanain Al-Talib … [et al.]

Al-Talib, Hassanain and Mohd Nasir, Nur Izzati Syamimi and Yaziz, Hafizuddin and Zulkafli, Nur Fatihah and Adani, Nur Aqidah and Noor Rashidi, Ahmad Ikhwan and Murugaiah, Chandrika and Shaari, Syahrul Azlin (2016) Potassium aluminium sulphate (Alum) inhibits growth of human axillary malodor-producing skin flora in vitro / Hassanain Al-Talib … [et al.]. Journal of Clinical and Health Sciences, 1 (1). pp. 59-63. ISSN 0127-984X


Introduction: Axillary malodor is caused by microbial biotransformation of non-smelling molecules present in apocrine secretions, into volatile odorous molecules. This study aimed to determine the antimicrobial activities of potassium aluminium salts (alum) against four malodor-producing axillary bacterial flora, as an alternative natural product for reducing axillary malodor. Methods: The antimicrobial activity of alum against axillary bacterial flora [Micrococcus luteus (ATCC 49732) (M. luteus), Staphylococcus epidermidis (ATCC 14990) (S. epidermidis), Corynebacterium xerosis (ATCC BAA-1293) C. xerosis and Bacilus subtilis (ATCC 19659) (B. subtilis)], was tested in vitro using broth dilution method for different concentrations (0.937 – 20mg/mL) on Luria-Bertani broth. Subculture was done to determine colony-forming units (CFUs) and the minimum inhibitory concentrations (MICs). Results: Alum showed excellent inhibitory effects on all tested bacteria. The lowest MIC of alum was against C. xerosis, at 1.88 mg/mL. M. luteus, B. subtilis and S.epidermidis showed a higher MIC of 3.75, 5.00 and 7.50 mg/mL, respectively. All of the tested bacteria were completely inhibited at a concentration of 7.50 mg/mL. Conclusions: This study revealed that alum has excellent antimicrobial effects against axillary malodor -producing bacteria and is recommended to be used either directly by topical application or as an active ingredient in deodorants and antiperspirants.


Item Type: Article
CreatorsEmail / ID. Num
Al-Talib, HassanainUNSPECIFIED
Mohd Nasir, Nur Izzati SyamimiUNSPECIFIED
Yaziz, HafizuddinUNSPECIFIED
Zulkafli, Nur FatihahUNSPECIFIED
Adani, Nur AqidahUNSPECIFIED
Noor Rashidi, Ahmad IkhwanUNSPECIFIED
Murugaiah, ChandrikaUNSPECIFIED
Shaari, Syahrul AzlinUNSPECIFIED
Subjects: R Medicine > RC Internal Medicine
R Medicine > RC Internal Medicine > Specialties of internal medicine
Divisions: Universiti Teknologi MARA, Shah Alam > Faculty of Medicine
Journal or Publication Title: Journal of Clinical and Health Sciences
Journal: UiTM Journal > Journal of Clinical and Health Sciences
ISSN: 0127-984X
Volume: 1
Number: 1
Page Range: pp. 59-63
Official URL: http://jchs-medicine.uitm.edu.my/
Item ID: 14924
Uncontrolled Keywords: Antimicrobial, Potassium aluminium, Alum, Malodorous, Axilla, JCHS, UiTM
URI: http://ir.uitm.edu.my/id/eprint/14924


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