Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.]

Daud, Norhayati and Mohd Noor, Nor Nafizah and Alimon, Hasimah and Abdul Rashid, Nursuhaidah (2015) Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.]. Esteem Academic Journal, 11 (1). pp. 109-116. ISSN 1675-7939

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Abstract

Sargassum polycystum is a species of brown algae (Phaeophyta). Some recent studies have found many uses of this algae, one of them is for medicine. In this study, crude hexane, dichloromethane and methanol extracts of Sargassum polycystum were tested for toxicity activity and screened for its principal chemical substances. The toxicity test was done using Brine Shrimp Lethality (BSL) test against Artemia salina Leach. The results of this study showed the LC50 value of methanol extract was 295.12 mgml-1, while both hexane and dichloromethane extracts were 275.42 mgml-1. The BSL test exhibited no significant toxicity against A.salina. Phytochemical screening shows S. polycystum contained non polar and polar components. As the conclusion, S. polycystum contained secondary metabolites that are not toxic to A. salina and they are not a potential source for toxicity.

Item Type: Article
Creators:
CreatorsID Num.
Daud, NorhayatiUNSPECIFIED
Mohd Noor, Nor NafizahUNSPECIFIED
Alimon, HasimahUNSPECIFIED
Abdul Rashid, NursuhaidahUNSPECIFIED
Subjects: Q Science > QH Natural history - Biology > Ecology > Toxicity testing
Q Science > QH Natural history - Biology > Ecology > Sea. Marine ecology. Ocean ecology
Divisions: Universiti Teknologi MARA, Pulau Pinang
Journal or Publication Title: Esteem Academic Journal
ISSN: 1675-7939
Volume: 11
Number: 1
Page Range: pp. 109-116
Item ID: 11997
Uncontrolled Keywords: Sargassum polycystum; toxicity test; phytochemical screening; BSL(Brine Shrimp Lethality) Test
Last Modified: 27 Jul 2016 00:36
Depositing User: Staf Pendigitalan 1
URI: http://ir.uitm.edu.my/id/eprint/11997

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