Determination of hydroquinone in skin whitening products by high performance liquid chromatography (HPLC) equipped with diode array detector (DAD) / Fatin Marzuki

Marzuki, Fatin (2016) Determination of hydroquinone in skin whitening products by high performance liquid chromatography (HPLC) equipped with diode array detector (DAD) / Fatin Marzuki. [Student Project] (Unpublished)

Abstract

Skin whitening products are being used widely, especially by women. However, not many people are aware that some of the ingredients used in skin whitening products were dangerous such as hydroquinone. Hydroquinone can cause skin irritation, redness and itching. A reverse phase - high performance liquid chromatography (HPLC) method was proposed here to detect the presence and determine the amount of hydroquinone in three different brands of skin whitening products which were labeled as X, Y and Z. A composition of methanol and water (65:55) with a flow rate 1.5 mL/min was used in this study. The results showed that hydroquinone was not detected in the samples X and Y under the condition used in this study. However, sample Z contained 0.14 ppm or 0.00698% of hydroquinone. The percent relative standard deviation (% RSD) of the sample Z was 14.86%. The detected amount of hydroquinone in sample Z was below the allowable limit, 20 ppm.

Metadata

Item Type: Student Project
Creators:
Creators
Email / ID Num.
Marzuki, Fatin
UNSPECIFIED
Contributors:
Contribution
Name
Email / ID Num.
UNSPECIFIED
Abdullah Munir, Zuraidah (Assoc. Prof.)
UNSPECIFIED
Subjects: K Law > K Law in general. Comparative and uniform law. Jurisprudence > Comparative law. International uniform Law > Food. Drugs. Cosmetics
Q Science > QD Chemistry > Physical and theoretical chemistry
Q Science > QD Chemistry > Analytical chemistry
Divisions: Universiti Teknologi MARA, Shah Alam > Faculty of Applied Sciences
Programme: Bachelor of Science (Hons) Chemistry (Forensic Analysis)
Keywords: Hydroquinone, Whitening products, Skin irritation, Redness, Itching
Date: 2016
URI: https://ir.uitm.edu.my/id/eprint/44464
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