Potassium aluminium sulphate (Alum) inhibits growth of human axillary malodor-producing skin flora in vitro / Hassanain Al-Talib … [et al.]

Al-Talib, Hassanain and Mohd Nasir, Nur Izzati Syamimi and Yaziz, Hafizuddin and Zulkafli, Nur Fatihah and Adani, Nur Aqidah and Noor Rashidi, Ahmad Ikhwan and Murugaiah, Chandrika and Shaari, Syahrul Azlin (2016) Potassium aluminium sulphate (Alum) inhibits growth of human axillary malodor-producing skin flora in vitro / Hassanain Al-Talib … [et al.]. Journal of Clinical and Health Sciences, 1 (1). pp. 59-63. ISSN 0127-984X


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Official URL: http://jchs-medicine.uitm.edu.my/


Introduction: Axillary malodor is caused by microbial biotransformation of non-smelling molecules present in apocrine secretions, into volatile odorous molecules. This study aimed to determine the antimicrobial activities of potassium aluminium salts (alum) against four malodor-producing axillary bacterial flora, as an alternative natural product for reducing axillary malodor. Methods: The antimicrobial activity of alum against axillary bacterial flora [Micrococcus luteus (ATCC 49732) (M. luteus), Staphylococcus epidermidis (ATCC 14990) (S. epidermidis), Corynebacterium xerosis (ATCC BAA-1293) C. xerosis and Bacilus subtilis (ATCC 19659) (B. subtilis)], was tested in vitro using broth dilution method for different concentrations (0.937 – 20mg/mL) on Luria-Bertani broth. Subculture was done to determine colony-forming units (CFUs) and the minimum inhibitory concentrations (MICs). Results: Alum showed excellent inhibitory effects on all tested bacteria. The lowest MIC of alum was against C. xerosis, at 1.88 mg/mL. M. luteus, B. subtilis and S.epidermidis showed a higher MIC of 3.75, 5.00 and 7.50 mg/mL, respectively. All of the tested bacteria were completely inhibited at a concentration of 7.50 mg/mL. Conclusions: This study revealed that alum has excellent antimicrobial effects against axillary malodor -producing bacteria and is recommended to be used either directly by topical application or as an active ingredient in deodorants and antiperspirants.

Item Type: Article
Uncontrolled Keywords: Antimicrobial, Potassium aluminium, Alum, Malodorous, Axilla, JCHS, UiTM
Subjects: R Medicine > RC Internal Medicine
R Medicine > RC Internal Medicine > Specialties of internal medicine
Divisions: Faculty of Medicine
Depositing User: Staf Pendigitan 1
Date Deposited: 11 Oct 2016 07:28
Last Modified: 27 Oct 2016 15:46
URI: http://ir.uitm.edu.my/id/eprint/14924

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