Chemical constituents of the insecticidal active extract of Tinospora crispa / Nor Aziyah Bakhari, Siti Nur Amirah Diana Fadzillah and Norain Isa

Bakhari, Nor Aziyah and Fadzillah, Siti Nur Amirah Diana and Isa, Norain (2013) Chemical constituents of the insecticidal active extract of Tinospora crispa / Nor Aziyah Bakhari, Siti Nur Amirah Diana Fadzillah and Norain Isa. Scientific Research Journal, 10 (1). pp. 23-35. ISSN 1675-7009

Official URL: https://srj.uitm.edu.my/

Abstract

Tinospora crispa Miers (Menispermaceae) is a climbing vine with stems rich in warts. The plant is called Akar Seruntum or Patawali in Malaysia and is widely used for treating skin complaints, malaria, bacterial abscess, high blood pressure and diabetes. In the present study, the stems of T. crispa were collected from the locality and succesively extracted with petroleum ether, followed by chloroform and
ethanol. The insecticidal active extract (ethanol extract) was subjected to column chromatography of silica gel eluted with a gradient mobile phase containing hexane, chloroform and ethanol. Among the chemical constituents isolated are n-tetracosyl trans-ferulate and n-octacosyl alcohol, along with three known aporphine alkaloids; N-formylnornuciferine, N-acetylnornuciferine and lysicamine. All compounds were identified by comparing their spectroscopic data (UV, IR, 1H NMR, MS) with data
from corresponding values in the literature. Isolation of n-tetracosyl trans-ferulate and n-octacosyl alcohol is reported the first time for T. crispa.

Metadata

Item Type: Article
Creators:
Creators
Email / ID Num.
Bakhari, Nor Aziyah
noraziyah140@ppinang.uitm.edu.my
Fadzillah, Siti Nur Amirah Diana
UNSPECIFIED
Isa, Norain
UNSPECIFIED
Subjects: Q Science > QK Botany > Menispermaceae (Moonseed)
Q Science > QK Botany > Plant physiology > Alkaloids
Divisions: Universiti Teknologi MARA, Shah Alam > Research Management Centre (RMC)
Journal or Publication Title: Scientific Research Journal
UiTM Journal Collections: UiTM Journal > Scientific Research Journal (SRJ)
ISSN: 1675-7009
Volume: 10
Number: 1
Page Range: pp. 23-35
Keywords: n-octacosyl alcohol, n-tetracosyl trans-ferulate, Tinospora crispa, aporphine alkaloid
Date: 2013
URI: https://ir.uitm.edu.my/id/eprint/13042
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13042

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